Grocery Outlet CMO Layla Kasha joins Yahoo Finance's Melody Hahm to discuss how the company is faring amid the COVID-19 pandemic, and what they're expecting in 2021.
Grocery Outlet CMO Layla Kasha joins Yahoo Finance's Melody Hahm to discuss how the company is faring amid the COVID-19 pandemic, and what they're expecting in 2021.
Amazing deals on table lamps for your workstation to cherry-pick your choice.
In the international market, the rate of gold decreased by 0.25 percent to USD 1,733.90 per ounce on Wednesday.
Conference Call and Live Audio Webcast Scheduled for Tomorrow, Wednesday, March 3, at 8:30 a.m. ET CELEBRATION, Fla., March 02, 2021 (GLOBE NEWSWIRE) -- KemPharm, Inc. (NASDAQ: KMPH), a specialty pharmaceutical company engaged in the discovery and development of proprietary prodrugs, today announced that the U.S. Food and Drug Administration (FDA) has approved the New Drug Application for (NDA) AZSTARYS™ (formerly referred to as KP415), a once-daily product for the treatment of attention deficit hyperactivity disorder (ADHD) in patients age six years and older. AZSTARYS consists of serdexmethylphenidate (SDX), KemPharm’s prodrug of d-methylphenidate (d-MPH), co-formulated with immediate-release d-MPH. Corium, Inc. (Corium), a portfolio company of Gurnet Point Capital (GPC), will lead the commercialization of AZSTARYS per the definitive collaboration and license agreement (the “License Agreement”) between KemPharm and an affiliate of GPC. Corium expects to make AZSTARYS commercially available in the U.S. as early as the second half of 2021. “The FDA approval of the AZSTARYS NDA is a transformational event for KemPharm and, we believe, an important advancement in the treatment of ADHD,” said Travis C. Mickle, Ph.D., President and CEO of KemPharm. “Today’s approval highlights both the value potential of SDX, our prodrug of d-MPH, and the ability of our LAT® platform technology to develop new prodrugs of approved medications that improve one or more of the attributes of the parent drug. We look forward to continuing our support of Corium as they forge ahead with the commercial launch of AZSTARYS.” “Today’s approval by the FDA is met with great excitement for this innovative new ADHD therapy and the potential it holds to meet the unmet needs of children, adolescents and adults,” said Perry Sternberg, CEO of Corium. “Our team is mobilized to put our commercial plans into action as the approval of the AZSTARYS NDA now enables us to finalize our preparations for commercial launch as early as the second half of this year.” Ann Childress, M.D., President of the Center for Psychiatry and Behavioral Medicine and an investigator in the AZSTARYS clinical trial, commented: “The ADHD industry, and specifically the MPH space, has seen little innovation in recent years, leaving prescribers and patients desiring new treatment options. In my research and practice, three properties are repeatedly cited by patients and their caregivers as being underserved by current ADHD medications: onset of action, duration of effect and consistency of therapy. Having investigated AZSTARYS and directly observed its clinical impact on patients, I believe this product will be an important new tool for physicians to use in providing effective care for patients with ADHD.” As a result of the FDA’s approval of the AZSTARYS NDA, KemPharm has earned a regulatory milestone payment following FDA approval as provided under the License Agreement, and KemPharm is working with GPC to evaluate the related provisions and amounts. Under the License Agreement, KemPharm may be eligible for up to $468 million in regulatory and sales milestone payments, as well as tiered royalty payments, on a product-by-product basis for net sales, with potential percentages up to the mid-twenties for U.S. net sales, and up to the mid-single digits of net sales in each country outside of the U.S. The complete label for AZSTARYS, including prescribing information and important safety information, may be found at www.kempharm.com/pipeline-products/#kp415. The complete label may also be downloaded in PDF format here: http://ml.globenewswire.com/Resource/Download/4f63af91-9427-40da-b881-82a5e22a0315. Conference Call Information: KemPharm will host a conference call and live audio webcast with slide presentation tomorrow, Wednesday, March 3, 2021, at 8:30 a.m. ET, to discuss FDA approval of the AZSTARYS NDA. Interested participants and investors may access the conference call by dialing either: (866) 395-2480 (U.S.)(678) 509-7538 (international)Conference ID: 4272912 An audio webcast with slide presentation will be accessible via the Investor Relations section of the Company’s website, http://investors.kempharm.com/. An archive of the webcast and presentation will be available for 90 days beginning tomorrow, March 3, 2021, at approximately 9:30 a.m. ET. About Attention Deficit Hyperactivity Disorder (ADHD): Attention-deficit/hyperactivity disorder (ADHD) is one of the most common mental disorders affecting children. ADHD also affects many adults. Symptoms of ADHD include inattention (not being able to keep focus), hyperactivity (excess movement that is not fitting to the setting) and impulsivity (hasty acts that occur in the moment without thought).1 An estimated 8.4% of children and 2.5% of adults have ADHD.23 The ADHD market accounted for approximately $17.9 billion of revenue in 2019 with a year-over-year prescription growth rate greater than four percent (4%). Within this, the branded portion of the ADHD market was approximately $7.4 billion in 2019, with extended-release products representing more than 97% of the branded prescriptions. In 2019, the methylphenidate segment of the ADHD market accounted for approximately 20 million prescriptions and $4.9 billion in sales. About AZSTARYSTM: AZSTARYSTM is an FDA-approved, once-daily product for the treatment of attention deficit hyperactivity disorder (ADHD) in patients age six years or older. AZSTARYS consists of SDX, KemPharm’s prodrug of d-methylphenidate (d-MPH), co-formulated with immediate release d-MPH. The complete approved prescribing information for AZSTARYS may be downloaded in PDF format here: http://ml.globenewswire.com/Resource/Download/4f63af91-9427-40da-b881-82a5e22a0315. About KemPharm: KemPharm is a specialty pharmaceutical company focused on the discovery and development of proprietary prodrugs to treat serious medical conditions through its proprietary LAT® (Ligand Activated Therapy) technology. KemPharm utilizes its proprietary LAT® technology to generate improved prodrug versions of FDA-approved drugs as well as to generate prodrug versions of existing compounds that may have applications for new disease indications. KemPharm’s product portfolio is highlighted by AZSTARYS™, an FDA-approved, once-daily treatment for attention deficit hyperactivity disorder (ADHD) which is based on serdexmethylphenidate, (SDX), KemPharm’s prodrug of d-methylphenidate (d-MPH). KemPharm is also advancing several clinical development candidates, including KP484 for the treatment of ADHD and KP879 for the treatment of Stimulant Use Disorder (SUD). AZSTARYS, KP484, and KP879 are all based on SDX. In addition, KemPharm has received FDA approval for APADAZ®, an immediate-release combination product containing benzhydrocodone, a prodrug of hydrocodone, and acetaminophen. For more information on KemPharm and its pipeline of prodrug product candidates visit www.kempharm.com or connect with us on Twitter, LinkedIn, Facebook and YouTube. Caution Concerning Forward Looking Statements: This press release may contain forward-looking statements made in reliance upon the safe harbor provisions of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. Forward-looking statements include all statements that do not relate solely to historical or current facts, including without limitation KemPharm’s proposed development and commercial timelines, and can be identified by the use of words such as “may,” “will,” “expect,” “project,” “estimate,” “anticipate,” “plan,” “believe,” “potential,” “should,” “continue” or the negative versions of those words or other comparable words. Forward-looking statements are not guarantees of future actions or performance. These forward-looking statements include statements about the commercial launch of AZSTARYS, including the timing of launch, the regulatory milestone payment, and the potential clinical benefits of AZSTARYS. These forward-looking statements are based on information currently available to KemPharm and its current plans or expectations and are subject to a number of uncertainties and risks that could significantly affect current plans. Risks concerning KemPharm’s business are described in detail in the “Risk Factors” sections of KemPharm’s Annual Report on Form 10-K for the year ended December 31, 2019, KemPharm’s Quarterly Report on Form 10-Q for the quarter ended September 30, 2020, and KemPharm’s other filings with the Securities and Exchange Commission. KemPharm is under no obligation to, and expressly disclaims any such obligation to, update or alter its forward-looking statements, whether as a result of new information, future events or otherwise. KemPharm Contacts: Jason Rando/Maureen McEnroe, CFATiberend Strategic Advisors, Inc.(212) 375-2665 / firstname.lastname@example.org@tiberend.com ________________________1 American Psychiatric Association (https://www.psychiatry.org/patients-families/adhd/what-is-adhd) 2 Danielson, ML, et al. Prevalence of Parent-Reported ADHD Diagnosis and Associated Treatment Among U.S. Children and Adolescents, 2016. Journal of Clinical Child & Adolescent Psychology, Volume 47, 2018 - Issue 23 Simon V , Czobor P, Bálint S , et al: :Prevalence and correlates of adult attention-deficit hyperactivity disorder: a meta-analysis. Br J Psychiatry194(3):204–211, 2009
And nope, they’re not sneakers
Today, we will review our financial results for the fourth quarter of fiscal 2020, as well as provide an outlook for the first quarter of fiscal 2021. Except for statements of historical fact, any remarks that we may make about our future expectations, plans, and prospects constitute forward-looking statements made pursuant to the Safe Harbor provisions of the Private Securities Litigation Reform Act of 1995.
URBN earnings call for the period ending January 31, 2021.
For the current season, LaLiga estimates a shortfall of 1.647 billion euros based on the 5.269 billion initially expected, representing a loss of 31 percent for Spain's top two divisions.
New York, New York--(Newsfile Corp. - March 2, 2021) - Squitieri & Fearon LLP today announced that it filed a class action seeking to represent stockholders of China XD Plastics Company Limited ("China XD") (NASDAQ : CXDC) who purchased their stock before September 30, 2020 (the "Class Period"). This action was filed in the Eastern District of New York and is captioned Joshua Schmitt, Individually and on Behalf of All Others Similarly Situated v. ...
GURUGRAM, India, March 02, 2021 (GLOBE NEWSWIRE) -- SpiceJet, the country’s favourite airline, has tied-up with WheelTug Plc for reserving 400 production slots for the state-of-the-art electric taxi system that will enable the airline in saving fuel, reducing CO2 emissions as well as noise levels, improve its fleet utilization thereby directly improving the company’s bottom line. The innovative WheelTug system places high-torque motors in the nose wheels of the aircraft. Pilots control the aircraft themselves, performing ground operations without requiring tugs for maneuvers. By keeping jet engines off in tight areas, the airline will lower its emissions. Additionally, SpiceJet gate and stand operations will be faster and more dependable helping the airline eliminate unexpected long delays affecting the schedule on any given day. “SpiceJet is a strong advocate for reducing carbon emissions. By inducting WheelTug into its B737 operations, the company aims to reduce the fuel burn during Taxi out and in,” said a SpiceJet spokesperson. SpiceJet is the largest Boeing 737 operator in India. Isaiah Cox, Chief Executive Officer, WheelTug said, "Signing SpiceJet at this time shows both companies are looking forward to a strong recovery for the industry as the world responds to the Covid-19 crisis.” “To that end, we also wish to recognize SpiceJet’s leading role in transporting vaccines to India.” About SpiceJet Ltd SpiceJet is India’s favourite airline that has made flying affordable for more Indians than ever before. The airline operates a fleet of Boeing 737s, Bombardier Q-400s & freighters and is the country’s largest regional player operating 63 daily flights under UDAN or the Regional Connectivity Scheme. The majority of the airline’s fleet offers SpiceMax, the most spacious economy class seating in India. The airline also operates a dedicated air cargo service under the brand name SpiceXpress offering safe, on-time, efficient and seamless cargo connectivity across India and on international routes. About WheelTug plc Based in the Isle of Man, WheelTug plc is developing the WheelTug aircraft electric drive system. More than 25 airlines representing 2000+ aircraft have reserved slots for WheelTug systems. www.wheeltug.com. Forward-looking statement: http://www.wheeltug.com/fls.shtml For more information: SpiceJet media contact: Tushar SrivastavaHead, Corporate Affairs & CSRtushar.email@example.com Anand DeoraSr. Manager –Corporate Communications+91 -98103 44335 firstname.lastname@example.org
Jamal Murray (Denver Nuggets) with a buzzer beater vs the Milwaukee Bucks, 03/02/2021
The travel logistics, as well as the economic consequences of playing an international tournament behind closed doors, have forced UEFA to consider contingency plans.
PJ Dozier (Denver Nuggets) with a deep 3 vs the Milwaukee Bucks, 03/02/2021
All you need to know about Gangubai Kathiawadi, the woman Alia Bhatt plays in Sanjay Leela Bhansali's next film.
However, Union Oil Minister Dharmendra Pradhan had last week said the petrol and diesel prices will fall towards end of winter.
12 years ago, Fong’s opened its first location in downtown Des Moines and became a popular spot for late-night dining.
DALLAS — Andrei Vasilevskiy stopped 28 shots for his third consecutive shutout, extending his scoreless streak to 200 minutes, and the Stanley Cup champion Tampa Bay Lightning beat the Dallas Stars 2-0 on Tuesday night. Vasilevskiy also held the struggling Stars without a goal four days earlier at home, a 5-0 win in the first meeting this season between the teams that played in the Stanley Cup Final in the NHL bubble last September. The three straight shutouts are a career best for Vasilevskiy, the 26-year-old goalie who has played all seven of his NHL seasons for Tampa Bay. Vasilevskiy surpassed his previous record scoreless streak of 184 minutes, 49 seconds, set three seasons ago, and is the 70th NHL goalie to surpass 200 minutes (200:45). His streak of 10-plus scoreless periods is the longest in the NHL this season. Just as they did against Dallas on Saturday, the Lightning went ahead to stay on a power-play goal in the first period by Ondrej Palat. Their other goal was an empty-netter by Yanni Gourde with five seconds left. Tampa Bay (15-4-1) has the NHL's longest active winning streak at five games and leads the Central Division with 31 points, one more than the Florida Panthers, who have played one more game than the Lightning. Dallas has won only once in its last 10 games. The Stars played at home for the first time since Feb. 13, before having four consecutive home games postponed because of extreme winter weather that led to extended power problems in North Texas and made the American Airlines Center unavailable. Anton Khudobin stopped 17 shots for Dallas. Palat scored 7 1/2 minutes into the game, and only 10 seconds after the Lightning went on the power play. After Palat's initial shot from the right side was blocked by Esa Lindell, the puck ricocheted across to captain Steven Stamkos on the other side. He passed to Victor Hedman in the middle and the puck went back to Palat for a one-timer between Khudobin and the right post. Andrew Cogliano had a point-blank shot for Dallas late in the first period, but it was pushed aside by Vasilevskiy. The Lightning goalie had also secured the puck after Joe Pavelski's shot was followed by captain Jamie Benn's two shots in quick succession. Benn had a shot midway through the second period that hit under Vasilevskiy's right arm, then ricocheted off the post. Vasilevskiy has stopped 92 consecutive shots, including 20 in his previous shutout of the Stars. POWER PALAT Palat's tally in the first period was his sixth power-play goal of the season, already a career high after only 20 games. His previous career best had been five over 56 games in 2016-17. It was also his NHL-best sixth time this season scoring the first goal of a game. STARS SCHEDULE The Stars played the first of 40 games over 70 days to finish out the reduced 56-game regular season. They came into the game off their last two-day break of the season, and started a seven-week stretch when they have games scheduled every Tuesday, Thursday, Saturday and Sunday through mid-April. Even after that, they aren't scheduled to have more than one day off between games, and will finish the regular season with seven consecutive road games over 12 days. WHAT’S NEXT Tampa Bay plays three games in four days at the Chicago Blackhawks, starting Thursday. Dallas stays at home for five more games, hosting Columbus on Thursday and Saturday. ___ More AP NHL coverage: https://apnews.com/hub/NHL and https://twitter.com/AP_Sports Stephen Hawkins, The Associated Press
Volvo expects half its global sales to come from electrified models by 2025.
St. Louis’ first-ever female mayor will be replaced by another woman, after city Treasurer Tishaura Jones and Alderwoman Cara Spencer on Tuesday bested two men in a new primary election format to advance to next month’s general election. Jones received 25,374 votes and Spencer was second with 20,649 votes, according to unofficial final results. Aldermanic President Lewis Reed was third, followed by businessman Andrew Jones. Incumbent Democrat Lyda Krewson chose not to seek a second four-year term. Tishaura Jones said on Zoom that St. Louisans “should be able to succeed here regardless of your skin colour, who you love, how you worship, your ZIP code, or any identity you have.” Spencer has been outspoken against special interests. She said on Facebook that her campaign “has changed the dialogue about how we serve St. Louis.” The city’s new “approval voting” format makes municipal contests nonpartisan and has another unique feature: Voters can “approve” of as many candidates in the primary as they want. Each vote counts as one. The idea is to get the two candidates with the most support to the general election, which is April 6. Four years ago, Tishaura Jones finished a close second to Krewson in the Democratic primary, and Reed was third. Krewson easily defeated Andrew Jones, a Republican, in the April 2017 general election to become the city's first woman mayor. Tishaura Jones and Andrew Jones are not related. Though this year's general election also will be nonpartisan, both Jones and Spencer are Democrats. The next mayor faces the daunting challenge of taming violent crime in a city that has been at or near the top of per capita homicide rankings for decades. Jones and Spencer, in interviews with The Associated Press last week, both said reducing violence was the top priority. Both pledged to address the underlying issues that lead to crime such as drug and alcohol addiction, poverty and mental illness. Jones, 48, is a former state representative who has been treasurer since 2013. She said the “arrest and incarcerate” model of criminal justice has been a failure. She would bring in more social workers, mental health counsellors and substance abuse counsellors, rather than adding more uniformed officers. Spencer, 42, has been a member of the Board of Aldermen since 2015. She favours a “focused deterrence” model connecting those at risk of committing violence to self-help resources, but making it clear those who cross into crime will face the consequences. Krewson, 67, had a personal connection to the violence -- her husband was fatally shot in a 1995 carjacking. She ran on a pledge to battle crime, but the city saw a staggering increase in killings during the coronavirus pandemic. Police said 262 people were killed in St. Louis last year — five less than the record of 267 set in 1993. But because the city’s population has declined since 1993, the homicide rate was much higher in 2020. In announcing her retirement from politics in November, Krewson said elections “are about the future.” She said at the time that challenges posed by crime, COVID-19 and other issues were not factors in her decision. In previous years, Democrats and Republicans squared off in separate primary elections in March. St. Louis is so heavily Democratic that the April general election was virtually irrelevant. Voters in November adopted the new “approval voting” method. St. Louis is just the second city to try it. Fargo, North Dakota, used it for the first time last year. Jim Salter, The Associated Press
Attorney General Christian Porter says he strongly rejects an allegation he raped a girl in 1988.
Sancho slotted home the winner after the visitors launched a counter-attack from their own area in the second half of the quarter-final at Borussia Park.