S&P 500 FUTURES SLIDE WITH FED'S POWELL IN SPOTLIGHT

U.S. central bank widely expected to keep rates at 23-year high later Wednesday

Prothena Corporation plc (PRTA)

NasdaqGS - NasdaqGS Real Time Price. Currency in USD

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20.34

-0.85

(-4.01%)

At close: 04:00PM EDT

20.73

+0.39

(+1.92%)

After hours:

04:56PM EDT