Yahoo Finance Sarepta Jumps After Pfizer's Rival Gene Therapy Flops In Phase 3 Test
Sarepta stock jumped Thursday after Pfizer's rival gene therapy for Duchenne muscular dystrophy failed in final-phase testing.
Sarepta stock jumped Thursday after Pfizer's rival gene therapy for Duchenne muscular dystrophy failed in final-phase testing.
TORONTO — Many people with diabetes in Canada will soon be able to take insulin once a week instead of daily, drug manufacturer Novo Nordisk announced on Monday.
(Bloomberg) -- The Food and Drug Administration delayed a breast- and lung-cancer trial of an experimental treatment that BioNTech SE licensed from Chinese biotech MediLink Therapeutics Ltd., citing safety concerns.Most Read from BloombergFlesh-Eating Bacteria That Can Kill in Two Days Spreads in JapanS&P 500 Hits 30th Record of 2024 as Megacaps Rally: Markets WrapThese Are the World’s Most Expensive Cities for Expats in 2024Hedge Funds’ Secret Weapon to Fight the SEC Lives in TexasHow the US Mo
Triple-negative breast cancer remains one of the most challenging forms of disease to treat due to the lack of known actionable biomarker targets, and chemotherapy-based regimens continue to be the mainstay of treatment, AstraZeneca said. The trial, known as CAPItello-290, was testing whether the drug combination improved overall survival in patients with inoperable or metastatic triple-negative breast cancer versus the older and cheaper chemotherapy agent, paclitaxel, in combination with a placebo.
The U.S. state of Kansas on Monday sued Pfizer, accusing the company of misleading the public about its COVID-19 vaccine by hiding risks while making false claims about its effectiveness. In a lawsuit filed in the District Court of Thomas County, the state said the New York-based drugmaker's alleged false statements violated the Kansas Consumer Protection Act. "Pfizer made multiple misleading statements to deceive the public about its vaccine at a time when Americans needed the truth," Kansas Attorney General Kris Kobach, a Republican, said in a statement.
The drug, an antibody-drug conjugate (ADC), was being studied in a trial sponsored by China-based MediLink, in patients with types of non-small cell lung cancer or breast cancer who have received prior forms of treatment. ADCs, often described as "guided-missile" cancer drugs, are designed to target only cancer cells, unlike conventional chemotherapy, potentially reducing damage to normal cells. The U.S. health regulator has shared with MediLink concerns that the drug, BNT326/YL202, may, at higher doses, expose humans to unreasonable and significant risk of illness or injuries.
Shares of the drug developer slumped about 30% to $5.88 in premarket trading. The drug, azenosertib, was being tested against solid tumors in an early-stage study and in patients with a type of ovarian and uterine cancer in two mid-stage studies. The regulator's decision comes after two patients in the ovarian cancer study died due to presumed sepsis, a condition where the body's immune system has an extreme response to an infection, the company said.
Genevieve Lane, who took Leqembi, died of a mysterious side effect called ARIA. Her death, and those of two other trial participants, have some doctors questioning whether the risks of the Alzheimer's drug are worth its benefits.
Harry Enten said it could point to "a historic moment" in American politics.
"'I’m so angry,' my second sister said, visibly shaking. 'I’m not kidding, I’m mad.' Our parents had been cruelest to her."
The late night host was nauseated by Trump's TMI description of his shower routine.
Here's an official lip reading of what the royals were talking about during Trooping the Colour 2024.
Jerry Seinfeld’s performance in Australia on Sunday was briefly derailed by an anti-Israel heckler who was mercilessly mocked by the comedian. “We have a genius ladies and gentlemen, he solved the Middle East,” Seinfeld joked as the crowd in Sydney jeered the heckler. As security moved to eject the person, he continued, “They’re going to start punching you in about three seconds, so I would try to get all of your genius out so we can all learn from you.” Read more at The Daily Beast.Get the Dail
With a two-year-old and another baby on the way, Cristina Ribeiro thought the house she and her family were renting in a quiet Milton subdivision would be a place for her children to grow.Now she's facing the prospect of moving out two weeks after she finishes recovering from a C-section, following a decision by the Landlord and Tenant Board — a decision she wants to ask the board to review on the grounds of discrimination against pregnancy and sex, as well as procedural problems.The board said
Mandel recounted the bloody scene to Kelly Ripa and Mark Consuelos.
Tight End University begins Monday and Chiefs star Travis Kelce’s annual camp will include a special concert this year.
TORONTO — A dispute at a business that conducts financial transactions escalated into a shooting that left three people – including the gunman – dead on Monday, Toronto police said as they investigated the incident that took place near a daycare and a school. Investigators said they responded to reports of gunshots shortly before 3:30 p.m. at a commercial building. Two men and a woman died, they said. "We believe that the individual responsible for the shooting is among the deceased," Det. Sgt.
Wondering if Prince Harry is heading to Balmoral in 2024? Here's what a "well placed source" had to say.
What are the "myths" about marriage that you wish you knew?
Leave it to Em Rata to make ballet-sneakers cool. See photos
The legendary pop singer attended an NYC screening for her new documentary, 'I Am: Celine Dion,' alongside her eldest son, René-Charles Angélil