UFC 266 predictions: Is anyone picking titles to change hands in upsets?

	Volkanovski vs. Ortega	Shevchenko vs. Murphy	Diaz vs. Lawler	Blaydes vs. Rozenstruik	Andrade vs. Calvillo
MMA Junkie readers’ consensus picks 2021: 147-90	volkanovski2021 Volkanovski (58%)	shevchenko2021 Shevchenko (95%)	diaz2021 Diaz (61%)	blaydes2021 Blaydes (71%)	andrade2021 Andrade (80%)
John Morgan @MMAjunkieJohn 2021: 152-85	volkanovski2021 Volkanovski	shevchenko2021 Shevchenko	lawler2021 Lawler	blaydes2021 Blaydes	andrade2021 Andrade
Simon Samano @SJSamano 2021: 147-90	volkanovski2021 Volkanovski	shevchenko2021 Shevchenko	lawler2021 Lawler	blaydes2021 Blaydes	andrade2021 Andrade
Ken Hathaway @kenshathaway 2021: 144-93 trophy copy 2018 Champion	volkanovski2021 Volkanovski	shevchenko2021 Shevchenko	diaz2021 Diaz	blaydes2021 Blaydes	calvillo2021 Calvillo
Nolan King @mma_kings 2021: 143-94	volkanovski2021 Volkanovski	shevchenko2021 Shevchenko	lawler2021 Lawler	blaydes2021 Blaydes	andrade2021 Andrade
Mike Bohn @MikeBohnMMA 2021: 142-95 trophy copy 2014 Champion	volkanovski2021 Volkanovski	shevchenko2021 Shevchenko	diaz2021 Diaz	blaydes2021 Blaydes	andrade2021 Andrade
Matt Erickson @MMAjunkieMatt 2021: 142-95	volkanovski2021 Volkanovski	shevchenko2021 Shevchenko	lawler2021 Lawler	blaydes2021 Blaydes	andrade2021 Andrade
Dan Tom @DanTomMMA 2021: 141-96 trophy copy 2020 Champion	volkanovski2021 Volkanovski	shevchenko2021 Shevchenko	diaz2021 Diaz	blaydes2021 Blaydes	andrade2021 Andrade
Danny Segura @dannyseguratv 2021: 137-100	volkanovski2021 Volkanovski	shevchenko2021 Shevchenko	diaz2021 Diaz	blaydes2021 Blaydes	andrade2021 Andrade
Brian Garcia @thegoze 2021: 135-102 trophy copy 2017 Champion	volkanovski2021 Volkanovski	shevchenko2021 Shevchenko	lawler2021 Lawler	blaydes2021 Blaydes	andrade2021 Andrade
George Garcia @MMAjunkieGeorge 2021: 135-102	ortega2021 Ortega	shevchenko2021 Shevchenko	diaz2021 Diaz	blaydes2021 Blaydes	calvillo2021 Calvillo
Farah Hannoun @Farah_Hannoun 2021: 134-103	volkanovski2021 Volkanovski	shevchenko2021 Shevchenko	diaz2021 Diaz	blaydes2021 Blaydes	andrade2021 Andrade
Abbey Subhan @kammakaze 2021: 132-105	volkanovski2021 Volkanovski	shevchenko2021 Shevchenko	lawler2021 Lawler	blaydes2021 Blaydes	calvillo2021 Calvillo
Matthew Wells @MrMWells 2021: 70-51	volkanovski2021 Volkanovski	shevchenko2021 Shevchenko	lawler2021 Lawler	blaydes2021 Blaydes	andrade2021 Andrade

A pair of UFC titles are on the line when the UFC returns to pay-per-view Saturday.

UFC 266 takes place at T-Mobile Arena in Las Vegas. The main card airs on pay-per-view following prelims on ESPNews and early prelims on ESPN+.

(Click here to open a PDF of the staff picks grid in a separate window.)

In the main event, featherweight champion Alexander Volkanovski (22-1 MMA, 9-0 UFC) takes on challenger Brian Ortega (15-1 MMA, 7-1 UFC). Volkanovski is a -190 favorite at Tipico. And only one of our 13 editors, writers, radio hosts and videographers is picking the +145 underdog Ortega to pull the upset.

In the co-feature, women’s flyweight champ Valentina Shevchenko (21-3 MMA, 10-2 UFC) is a massive -1800 favorite against challenger Lauren Murphy (15-4 MMA, 7-4 UFC). Not surprisingly, Shevchenko is one of two unanimous picks on our main card.

Also on the main card, Nick Diaz (26-9 MMA, 7-6 UFC) returns for the first time in nearly seven years to take on former welterweight champ Robbie Lawler (28-15 MMA, 13-9 UFC) in a rematch at middleweight. Lawler is a -155 favorite, but he’s only got a 7-6 lead in the picks.

Our other unanimous pick is at heavyweight. Curtis Blaydes (14-3 MMA, 9-3 UFC) is a -340 favorite against Jairzinho Rozenstruik (12-2 MMA, 6-2 UFC), and he pitched a 13-0 shutout in the picks.

And to open the main card, former women’s strawweight champ Jessica Andrade (21-9 MMA, 12-7 UFC) is a -270 favorite at flyweight against Cynthia Calvillo (9-2-1 MMA, 6-2-1 UFC). Andrade has a big 10-3 lead in the picks.

In the MMA Junkie reader consensus picks, Volkanovski (58 percent), Shevchenko (95 percent), Diaz (61 percent), Blaydes (71 percent) and Andrade (80 percent) are the choices.

Check out all the picks above.

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