Joshua puts his WBA, IBF, WBO and IBO belts on the line in the first fight ever to take place at the Tottenham Hotspur Stadium.
More than 60,000 fans are expected to be in attendance as Joshua attempts to navigate his way past a tough mandatory assignment and remain on track for a mammoth all-British unification double-header against Tyson Fury, which was close to being signed off for 2021 before an arbitrary hearing ruled that the latter must instead fight Deontay Wilder for the third time.
The Briton should be in for a stern examination against fellow London 2012 Olympic gold medallist Usyk, who is a former undisputed cruiserweight champion of the world looking to make a significant statement in only his third bout in the heavyweight ranks.
How to watch Joshua vs Usyk
TV channel: In the UK, Joshua vs Usyk is available to watch via pay-per-view on Sky Sports Box Office at a cost of £24.95.
Live stream: Those that have purchased the fight can also watch live online via the downloadable player or Sky Sports Box Office app.