A seriously ill two-year-old girl has died after her life support machine was switched off with her "parents by her side", a family spokeswoman has said.
Alta Fixsler had a brain injury at birth and had been in hospital since the day she was born, with doctors saying she had no chance of recovery.
Earlier this month, her parents lost a court fight over where life-support treatment could be withdrawn from her.
Alta's family press officer confirmed the "sad news" to Sky News reporter Sadiya Chowdhury on Monday night.
"Sad news, little Alta Fixsler's life support was turned off this afternoon and she died at the hospice with her parents by her side," the press officer said.
A judge ruled in May that it was not in Alta's best interest for Manchester University NHS Foundation Trust to continue life-sustaining treatment.
He also concluded she should not be taken to Israel and turned down the parents' request.
Chaya and Abraham Fixsler argued the decision was against their rights as parents and their faith as Hasidic Jews.
The couple had been fighting with the care provider to bring Alta back to their home in Salford for the end of her treatment.
But hospital bosses said treatment should be withdrawn in hospital or at a hospice.
Mr Justice MacDonald ruled that it was in Alta's best interests that treatment should be withdrawn in a children's hospice.
He added: "I am satisfied that this option best accommodates Alta's welfare need for specialist care at the end of her life under a reliable, safe and sustainable system of high calibre care protected from disruption, whilst allowing, in so far as possible and consistent with Alta's best interests, the family and the community to perform the sacred religious obligations of the Orthodox Jewish faith."
But the family said the hospital was 25 minutes drive from their home and argued they could not always visit their daughter when the hospital called with any concerns.
They also worried about missing the final moments of their daughter's life if she was not at home with them when the treatment ended.
Ms Fixsler previously told Sky News: "I want to take her home, we love her, we want her, and I want to give her everything I can."