| Top Institutional Holders |
|---|
| Holder | Shares | % Out | Value* | Reported |
|---|
| Passport Capital, LLC | 9,554,858 | 9.49 | 105,103,438 | 2013-03-31 | | First Manhattan Company | 8,479,184 | 8.42 | 93,271,024 | 2013-03-31 | | QVT Financial LP | 8,346,697 | 8.29 | 91,813,667 | 2013-03-31 | | Vanguard Group, Inc. (The) | 5,492,943 | 5.46 | 60,422,373 | 2013-03-31 | | Meditor Group Ltd | 4,207,296 | 4.18 | 46,280,256 | 2013-03-31 | | BlackRock Fund Advisors | 3,601,541 | 3.58 | 39,616,951 | 2013-03-31 | | State Street Corporation | 3,459,712 | 3.44 | 38,056,832 | 2013-03-31 | | BlackRock Institutional Trust Company, N.A. | 2,739,515 | 2.72 | 30,134,665 | 2013-03-31 | | Chilton Investment Company, LLC | 2,450,371 | 2.43 | 26,954,081 | 2013-03-31 | | Tahithromos, LLC | 2,175,193 | 2.16 | 23,927,123 | 2013-03-31 |
|
| Holder | Shares | % Out | Value* | Reported |
|---|
| Vanguard Small-Cap Index Fund | 1,666,297 | 1.66 | 22,361,705 | 2012-12-31 | | iShares Russell 2000 Index Fund | 1,602,589 | 1.59 | 17,628,479 | 2013-03-31 | | Federated Kaufmann Fund | 1,350,000 | 1.34 | 16,348,500 | 2013-01-31 | | SPDR (R) Ser Tr-SPDR (R) S&P (R) Pharmaceuticals ETF | 1,344,053 | 1.34 | 14,784,583 | 2013-03-31 | | Vanguard Total Stock Market Index Fund | 1,332,224 | 1.32 | 17,878,446 | 2012-12-31 | | Vanguard Small-Cap Growth Index Fund | 1,172,819 | 1.17 | 15,739,230 | 2012-12-31 | | Powershares Exhg Traded Fd-Dynamic Pharmaceuticals Port | 906,232 | 0.90 | 9,968,552 | 2013-03-31 | | Vanguard Extended Market Index Fund | 844,564 | 0.84 | 11,334,048 | 2012-12-31 | | iShares Russell 2000 Growth Index Fund | 731,741 | 0.73 | 8,049,151 | 2013-03-31 | | iShares NASDAQ Biotechnology Index Fund | 716,392 | 0.71 | 7,880,312 | 2013-03-31 |
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View Transactions for Insiders & Institutional Holders Value shown is computed using the security's price on the report date given. Currency in USD. |