| Top Institutional Holders |
|---|
| Holder | Shares | % Out | Value* | Reported |
|---|
| UBS Global Asset Management (Americas) Inc | 1,703,560 | 8.42 | 45,399,874 | 2013-03-31 | | Park West Asset Management LLC | 1,504,605 | 7.44 | 40,097,723 | 2013-03-31 | | Knott (David M.) | 1,452,566 | 7.18 | 38,710,883 | 2013-03-31 | | Arbor Capital Management, LLC | 890,771 | 4.40 | 23,739,047 | 2013-03-31 | | Wellington Management Company, LLP | 782,926 | 3.87 | 20,864,977 | 2013-03-31 | | Vanguard Group, Inc. (The) | 708,635 | 3.50 | 18,885,122 | 2013-03-31 | | BlackRock Fund Advisors | 638,424 | 3.16 | 17,013,999 | 2013-03-31 | | BlackRock Institutional Trust Company, N.A. | 577,638 | 2.85 | 15,394,052 | 2013-03-31 | | Deutsche Bank Aktiengesellschaft | 534,535 | 2.64 | 14,245,357 | 2013-03-31 | | BVF Inc. | 3,621,665 | 17.90 | 96,517,372 | 2013-03-31 |
|
| Holder | Shares | % Out | Value* | Reported |
|---|
| Fidelity Select Portfolios - Biotechnology | 614,503 | 3.04 | 16,788,221 | 2013-04-30 | | iShares Russell 2000 Index Fund | 274,443 | 1.36 | 7,497,782 | 2013-04-30 | | Vanguard Total Stock Market Index Fund | 269,367 | 1.33 | 7,178,630 | 2013-03-31 | | Vanguard Extended Market Index Fund | 212,082 | 1.05 | 5,651,985 | 2013-03-31 | | iShares NASDAQ Biotechnology Index Fund | 206,904 | 1.02 | 5,652,617 | 2013-04-30 | | Vanguard Small-Cap Growth Index Fund | 132,658 | 0.66 | 3,535,335 | 2013-03-31 | | iShares Russell 2000 Growth Index Fund | 120,509 | 0.60 | 3,292,305 | 2013-04-30 | | Delaware Group Equity Fds IV-Delaware Healthcare Fund | 100,000 | 0.49 | 2,665,000 | 2013-03-31 | | College Retirement Equities Fund-Stock Account | 66,749 | 0.33 | 1,778,860 | 2013-03-31 | | Spartan Extended Market Index Fund | 57,627 | 0.28 | 1,574,369 | 2013-04-30 |
|
View Transactions for Insiders & Institutional Holders Value shown is computed using the security's price on the report date given. Currency in USD. |
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