| Top Institutional Holders |
|---|
| Holder | Shares | % Out | Value* | Reported |
|---|
| Warburg Pincus LLC | 2,460,807 | 9.92 | 8,563,608 | 2013-03-31 | | BAMCO Inc. | 1,590,900 | 6.41 | 5,536,332 | 2013-03-31 | | Oppenheimer Funds, Inc. | 1,359,927 | 5.48 | 4,732,545 | 2013-03-31 | | I.G. Investment Management, Ltd | 1,359,203 | 5.48 | 4,730,026 | 2013-03-31 | | Wellington Management Company, LLP | 1,264,295 | 5.10 | 4,399,746 | 2013-03-31 | | BMO Financial Corp | 733,569 | 2.96 | 2,552,820 | 2013-03-31 | | Artal Group S.A. | 4,192,167 | 16.90 | 14,588,741 | 2013-03-31 | | Tekla Capital Management LLCC. | 426,481 | 1.72 | 1,484,153 | 2013-03-31 | | Gabelli Funds, LLC | 240,000 | 0.97 | 835,200 | 2013-03-31 | | BlackRock Fund Advisors | 152,010 | 0.61 | 528,994 | 2013-03-31 |
|
| Holder | Shares | % Out | Value* | Reported |
|---|
| Oppenheimer International Growth Fund | 1,262,894 | 5.09 | 5,064,204 | 2013-02-28 | | Baron Growth Fund | 1,150,000 | 4.64 | 5,221,000 | 2012-12-31 | | H&Q Healthcare Investors | 258,025 | 1.04 | 1,171,433 | 2012-12-31 | | ING Partners Inc.-ING Baron Small Cap Growth Portfolio | 254,000 | 1.02 | 883,920 | 2013-03-31 | | Gabelli Small Cap Growth Fund | 240,000 | 0.97 | 835,200 | 2013-03-31 | | H&Q Life Sciences Investors | 168,456 | 0.68 | 764,790 | 2012-12-31 | | Lincoln VIP Tr-Baron Growth Opportunities Fund | 135,000 | 0.54 | 612,900 | 2012-12-31 | | iShares Russell 2000 Index Fund | 95,745 | 0.39 | 333,192 | 2013-03-31 | | MassMutual Premier International Equity Fund | 87,393 | 0.35 | 396,764 | 2012-12-31 | | Manning & Napier Inflation Focus Equity Series Fund | 49,640 | 0.20 | 172,747 | 2013-03-31 |
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View Transactions for Insiders & Institutional Holders Value shown is computed using the security's price on the report date given. Currency in USD. |