| Top Institutional Holders |
|---|
| Holder | Shares | % Out | Value* | Reported |
|---|
| Vanguard Group, Inc. (The) | 2,856,705 | 4.59 | 69,617,900 | 2013-03-31 | | UBS Global Asset Management (Americas) Inc | 2,616,913 | 4.21 | 63,774,169 | 2013-03-31 | | BlackRock Fund Advisors | 1,849,500 | 2.97 | 45,072,315 | 2013-03-31 | | Healthcor Management LP | 1,825,000 | 2.94 | 33,306,250 | 2012-12-31 | | Capital World Investors | 1,700,000 | 2.73 | 31,025,000 | 2012-12-31 | | State Street Corporation | 1,658,560 | 2.67 | 40,419,107 | 2013-03-31 | | BlackRock Institutional Trust Company, N.A. | 1,512,684 | 2.43 | 36,864,109 | 2013-03-31 | | Bridger Management LLC | 1,366,648 | 2.20 | 33,305,211 | 2013-03-31 | | FMR LLC | 7,862,160 | 12.65 | 143,484,420 | 2012-12-31 | | Deerfield Management | 1,221,400 | 1.96 | 29,765,518 | 2013-03-31 |
|
| Holder | Shares | % Out | Value* | Reported |
|---|
| Fidelity Growth Company Fund | 4,307,058 | 6.93 | 104,963,003 | 2013-03-31 | | Smallcap World Fund | 1,700,000 | 2.73 | 41,429,000 | 2013-03-31 | | Fidelity Select Portfolios - Biotechnology | 1,583,803 | 2.55 | 38,597,279 | 2013-03-31 | | iShares Russell 2000 Index Fund | 882,676 | 1.42 | 21,510,814 | 2013-03-31 | | Lord Abbett Developing Growth Fund | 835,302 | 1.34 | 20,155,837 | 2013-01-31 | | Fidelity Dividend Growth Fund | 813,400 | 1.31 | 19,822,558 | 2013-03-31 | | Vanguard Small-Cap Index Fund | 781,103 | 1.26 | 14,255,129 | 2012-12-31 | | Prudential Jennison Health Sciences Fd | 654,613 | 1.05 | 15,952,918 | 2013-03-31 | | SPDR (R) Ser Tr-SPDR (R) S&P (R) Biotech ETF | 653,773 | 1.05 | 15,932,448 | 2013-03-31 | | Price (T.Rowe) Health Sciences Fund | 653,200 | 1.05 | 15,918,484 | 2013-03-31 |
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View Transactions for Insiders & Institutional Holders Value shown is computed using the security's price on the report date given. Currency in USD. |