| Date |
Insider |
Shares |
Transaction |
Value* |
| 20-Dec-07 |
ELCHICO JOSEFINA T Officer
|
400 |
Sale at $3.90 per share. |
$1,560 |
| 18-Dec-07 |
GONZALEZ ALEJANDRO Beneficial Owner (10% or more)
|
50,000 |
Purchase at $3.93 per share. |
$196,500 |
| 14-Dec-07 |
GONZALEZ ALEJANDRO Beneficial Owner (10% or more)
|
57,508 |
Purchase at $3.65 per share. |
$209,904 |
| 12-Sep-07 |
GONZALEZ ALEJANDRO Beneficial Owner (10% or more)
|
75,000 |
Purchase at $4.45 per share. |
$333,750 |
| 11-Sep-07 |
GONZALEZ ALEJANDRO Beneficial Owner (10% or more)
|
10,000 |
Purchase at $4.45 - $4.45 per share. |
$45,0002
|
| 31-Aug-07 |
GONZALEZ ALEJANDRO Beneficial Owner (10% or more)
|
13,000 |
Purchase at $4.27 - $4.27 per share. |
$56,0002
|
| 14-Jun-07 |
GONZALEZ ALEJANDRO Beneficial Owner (10% or more)
|
400,000 |
Purchase at $4.59 - $4.65 per share. |
$1,848,0002
|
| 4-Apr-07 |
TOPPER JAMES N Director
|
833,333 |
Purchase at $6 - $6 per share. |
$5,000,0002
|
| 4-Apr-07 |
NAINI NADER J Director
|
833,333 |
Purchase at $6 - $6 per share. |
$5,000,0002
|
| 4-Apr-07 |
SUTTER MARTIN P Director
|
1,000,000 |
Purchase at $6 - $6 per share. |
$6,000,0002
|
| 4-Apr-07 |
ESSEX WOODLANDS HEALTH VENTURES FUND VI L P Beneficial Owner (10% or more)
|
1,000,000 |
Purchase at $6 - $6 per share. |
$6,000,0002
|
| 4-Apr-07 |
GONZALEZ ALEJANDRO Beneficial Owner (10% or more)
|
833,333 |
Purchase at $6 - $6 per share. |
$5,000,0002
|
| 3-Apr-07 |
FRAZIER HEALTHCARE V, LP Beneficial Owner (10% or more)
|
833,333 |
Purchase at $6 - $6 per share. |
$5,000,0002
|
| 15-Mar-07 |
SMITH CRAIG R Director
|
3,600 |
Acquisition (Non Open Market) at $0 per share. |
N/A |
| 22-Feb-07 |
SEIKKULA LUKE Officer
|
2,718 |
Statement of Ownership |
N/A |
| 5-Feb-07 |
TANSEY MICHAEL JAMES BYRON Officer
|
1,900 |
Purchase at $3.10 - $3.11 per share. |
$5,8992
|
| 10-Jan-07 |
KOCH LISA I Officer
|
652 |
Automatic Sale at $3.02 - $3.02 per share. |
$1,9692
|
| 10-Jan-07 |
JENN PAUL Officer
|
6,630 |
Automatic Sale at $3.09 - $3.09 per share. |
$20,0002
|
| 9-Jan-07 |
KOCH LISA I Officer
|
3,500 |
Automatic Sale at $3.05 - $3.05 per share. |
$11,0002
|
| 3-Jan-07 |
KOCH LISA I Officer
|
1,181 |
Automatic Sale at $3.02 - $3.02 per share. |
$3,5662
|
| 31-Dec-06 |
ELCHICO JOSEFINA T Officer
|
1,736 |
Acquisition (Non Open Market) at $2.58 per share. |
$4,478 |
| 31-Dec-06 |
WISEMAN ANDREW Officer
|
155 |
Acquisition (Non Open Market) at $2.58 - $2.58 per share. |
$3992
|
| 31-Dec-06 |
SLOAN GAIL A Officer
|
159 |
Acquisition (Non Open Market) at $2.58 - $2.58 per share. |
$4102
|
| 31-Dec-06 |
KOCH LISA I Officer
|
251 |
Acquisition (Non Open Market) at $2.58 - $2.58 per share. |
$6472
|
| 31-Dec-06 |
JENN PAUL Officer
|
176 |
Acquisition (Non Open Market) at $2.58 - $2.58 per share. |
$4542
|
| 29-Dec-06 |
GONZALEZ ALEJANDRO Beneficial Owner (10% or more)
|
25,000 |
Purchase at $3.12 - $3.12 per share. |
$78,0002
|
| 29-Dec-06 |
JENN PAUL Officer
|
5,000 |
Automatic Sale at $3.11 - $3.11 per share. |
$16,0002
|
| 27-Dec-06 |
LINNIK MATTHEW D Officer
|
365 |
Automatic Sale at $3.03 - $3.03 per share. |
$1,1052
|
| 27-Dec-06 |
GONZALEZ ALEJANDRO Beneficial Owner (10% or more)
|
8,600 |
Purchase at $3.12 - $3.12 per share. |
$27,0002
|
| 26-Dec-06 |
GONZALEZ ALEJANDRO Beneficial Owner (10% or more)
|
500 |
Purchase at $3.08 - $3.08 per share. |
$1,5402
|
| 22-Dec-06 |
GONZALEZ ALEJANDRO Beneficial Owner (10% or more)
|
40,200 |
Purchase at $2.92 - $2.92 per share. |
$117,0002
|
| 21-Dec-06 |
LINNIK MATTHEW D Officer
|
5,000 |
Automatic Sale at $2.88 - $2.88 per share. |
$14,0002
|
| 21-Dec-06 |
GONZALEZ ALEJANDRO Beneficial Owner (10% or more)
|
20,000 |
Purchase at $2.88 - $2.88 per share. |
$58,0002
|
| 20-Dec-06 |
LINNIK MATTHEW D Officer
|
2,500 |
Automatic Sale at $3 - $3 per share. |
$7,5002
|
| 19-Dec-06 |
LINNIK MATTHEW D Officer
|
3,500 |
Automatic Sale at $3.01 - $3.01 per share. |
$11,0002
|
| 18-Dec-06 |
SMITH CRAIG R Director
|
3,600 |
Acquisition (Non Open Market) at $2.99 - $2.99 per share. |
$11,0002
|
| 18-Dec-06 |
LINNIK MATTHEW D Officer
|
7,500 |
Automatic Sale at $3.02 - $3.02 per share. |
$23,0002
|
| 14-Dec-06 |
LINNIK MATTHEW D Officer
|
1,500 |
Automatic Sale at $3.12 - $3.12 per share. |
$4,6802
|
| 14-Dec-06 |
JENN PAUL Officer
|
1,500 |
Automatic Sale at $3.12 - $3.12 per share. |
$4,6802
|
| 17-Oct-06 |
GONZALEZ ALEJANDRO Beneficial Owner (10% or more)
|
15,000 |
Purchase at $3.56 - $3.56 per share. |
$53,0002
|
| 16-Oct-06 |
GONZALEZ ALEJANDRO Beneficial Owner (10% or more)
|
15,000 |
Purchase at $3.40 - $3.4 per share. |
$51,0002
|
| 13-Oct-06 |
GONZALEZ ALEJANDRO Beneficial Owner (10% or more)
|
20,000 |
Purchase at $3.18 - $3.18 per share. |
$64,0002
|
| 30-Sep-06 |
ELCHICO JOSEFINA T Officer
|
1,736 |
Acquisition (Non Open Market) at $3.06 - $3.06 per share. |
$5,3122
|
| 30-Sep-06 |
WISEMAN ANDREW Officer
|
153 |
Acquisition (Non Open Market) at $3.06 - $3.06 per share. |
$4682
|
| 30-Sep-06 |
SLOAN GAIL A Officer
|
156 |
Acquisition (Non Open Market) at $3.06 - $3.06 per share. |
$4772
|
| 30-Sep-06 |
KOCH LISA I Officer
|
247 |
Acquisition (Non Open Market) at $3.06 - $3.06 per share. |
$7552
|
| 30-Sep-06 |
JENN PAUL Officer
|
174 |
Acquisition (Non Open Market) at $3.06 - $3.06 per share. |
$5322
|
| 24-Aug-06 |
JENN PAUL Officer
|
1,819 |
Disposition (Non Open Market) at $0 per share. |
N/A |
| 1-Jul-06 |
SLOAN GAIL A Officer
|
2,230 |
Acquisition (Non Open Market) |
N/A |
| 30-Jun-06 |
ELCHICO JOSEFINA T Officer
|
1,736 |
Acquisition (Non Open Market) at $3.06 - $3.06 per share. |
$5,3122
|
| 30-Jun-06 |
WISEMAN ANDREW Officer
|
131 |
Acquisition (Non Open Market) at $3.06 - $3.06 per share. |
$4002
|
| 30-Jun-06 |
SLOAN GAIL A Officer
|
278 |
Acquisition (Non Open Market) at $3.06 - $3.06 per share. |
$8502
|
| 30-Jun-06 |
KOCH LISA I Officer
|
211 |
Acquisition (Non Open Market) at $3.06 - $3.06 per share. |
$6452
|
| 30-Jun-06 |
JENN PAUL Officer
|
148 |
Acquisition (Non Open Market) at $3.06 - $3.06 per share. |
$4522
|
| 18-May-06 |
KOCH LISA I Officer
|
10,974 |
Statement of Ownership |
N/A |
| 8-May-06 |
GONZALEZ ALEJANDRO Beneficial Owner (10% or more)
|
47,272 |
Purchase at $3.95 - $3.95 per share. |
$187,0002
|
| 31-Mar-06 |
BENNETT BRUCE K JR Officer
|
185 |
Acquisition (Non Open Market) at $3.06 - $3.06 per share. |
$5662
|
| 31-Mar-06 |
JENN PAUL Officer
|
174 |
Acquisition (Non Open Market) at $3.06 - $3.06 per share. |
$5322
|
| 31-Mar-06 |
REILLY TEDDI Officer
|
164 |
Acquisition (Non Open Market) at $3.06 - $3.06 per share. |
$5012
|
| 31-Mar-06 |
SLOAN GAIL A Officer
|
156 |
Acquisition (Non Open Market) at $3.06 - $3.06 per share. |
$4772
|
| 31-Mar-06 |
WISEMAN ANDREW Officer
|
153 |
Acquisition (Non Open Market) at $3.06 - $3.06 per share. |
$4682
|
| 31-Mar-06 |
ELCHICO JOSEFINA T Officer
|
1,736 |
Acquisition (Non Open Market) at $3.06 - $3.06 per share. |
$5,3122
|
| 15-Mar-06 |
SMITH CRAIG R Director
|
20,000 |
Acquisition (Non Open Market) at $0 per share. |
N/A |